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The subject of intentional breeding or meat rabbits is prohibited. The answers provided on this board are for general guideline purposes only. The information is not intended to diagnose or treat your pet.  It is your responsibility to assess the information being given and seek professional advice/second opinion from your veterinarian and/or qualified behaviorist.

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Forum HOUSE RABBIT Q & A Mange Treatment Problems

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    • JoyceB139
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        Dear All – We are struggling with finding a cure for Fluffy, our Dutch rabbit, and would appreciate any thoughts. He was diagnosed with sarcoptic mange, but nothing seems to be working. He took an Ivermectin shot every two weeks for the last eight weeks, but it has not resolved the problem. His area and bedding were regularly cleaned and changed during treatment, but this has not helped. His companion has not been infected and they have been kept apart for the time being.  Fluffy improved slightly after each shot of Ivermectin, but then starts itching again shortly thereafter and the crusts increase. On our visit last week, the veterinarian switched to Selamectin, which he applied topically between his shoulder blades, but that has not had any effect and he has worsened in the interim. The veterinarian suspects that he may have developed resistance to Ivermectin, which is the drug of choice for this condition. We have another appointment in a couple of days and the veterinarian said that he would try another drug related to Ivermectin, to see if that would give a positive result. We’re not yet aware of the drug that he will administer during the next visit. We also don’t have many choices for veterinarians in our area. Any thoughts or recommendations would be highly appreciated as we can’t stand his suffering and are feeling helpless. Many thanks.


      • Bam
        Moderator
        16838 posts Send Private Message

          I’m sorry to hear this. Ivermectin and selamectin are the drugs of choice for mange. Selamectin is considered the more effective of the two. It’s not the rabbit that develops resistance to a drug, it’s the parasite that becomes resistant.
          I don’t know a better drug for mange, I hope the selamectin will show effect or that the next one you try will be more effective.
          Sometimes you treat rabbit parasites with both oral and injectable ivermectin at the same time, although it’s doubtful if that does any good, there’s some evidence to the contrary.
          Sarcoptic mange involves an allergic reaction to the parasites, so an antihistamine could help with the itching. Allergies can manifest themselves rather a long time after the responsible parasite has been eradicated, and if the person/animal is very sensitive, really really small particles of the allergen can elicit an allergic response. Benadryl for children can be used with rabbits, but there should be other safe antihistamines as well, there are more modern types that don’t act as sedatives.


        • jerseygirl
          Moderator
          22338 posts Send Private Message

            The vet took a sample to indentify the species of parasite?

            Posted By JoyceB139 on 8/22/2016 5:07 PM
            … Fluffy improved slightly after each shot of Ivermectin, but then starts itching again shortly thereafter and the crusts increase. …

            It’s possible there is a bacterial or fungal infection also.

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        Forum HOUSE RABBIT Q & A Mange Treatment Problems